What Enhertu Side Effects Actually Feel Like (From Inside My Body)

When my doctor listed the side effects, I nodded.

Fatigue.

Nausea.

Hair loss.

They sounded manageable.

What I didn’t understand was how much they would change the way I move through a day.

Not dramatically.

Just quietly.

Constantly.

This is what it’s really like.

The tired that lives in your bones

I wake up tired.

Not sleepy — tired.

Like my body already ran a marathon before I even opened my eyes.

Some days I sit down “just for a minute” and realize an hour passed.

Some days holding my phone feels heavy.

It’s not laziness.

It’s my body working overtime.

Food is… weird now

Nothing sounds good.

Things I loved smell wrong.

Sometimes water tastes like metal.

I eat because I know I should, not because I want to.

My stomach never feels settled —

it’s either bloated, cramping, constipated, or doing the opposite.

There is no normal.

My body feels unfamiliar

It’s not just the hair on my head.

My brows thinned.

My lashes fell out.

My skin feels sensitive and dry.

My nails bend and peel.

I look in the mirror and see someone I recognize… but don’t feel like.

That part hurts more than I expected.

The nerve stuff nobody explains

My feet tingle.

My hands feel numb sometimes.

Random little zaps run through my legs.

Some days it feels like my body is glitching.

The brain fog is real

I forget what I was saying mid-sentence.

I walk into rooms and don’t know why.

I stare at my phone without remembering what I picked it up for.

It’s embarrassing.

And frustrating.

And hard to explain.

The breathing thing scares me

Climbing stairs feels harder.

My chest feels heavy some days.

It makes you very aware of every breath.

That awareness sticks with you.

The part that isn’t on the list

I cry easier.

I get irritated faster.

I feel disconnected from my old life.

I feel guilty for resting.

Guilty for canceling.

Guilty for needing help.

And then I feel guilty for feeling guilty.

A Mojo moment 🐾

When I lie down because my body feels like too much, Mojo curls up against me without moving.

He doesn’t care that I’m tired or slow or quiet.

He just stays.

And honestly, some days that’s enough.

If you’re on Enhertu too

You’re not imagining this.

You’re not being dramatic.

You’re not weak.

Your body is doing something hard.

And you deserve grace while it does.

💌 Subscribe to Mojo & The Mess if you want real, honest stories from someone walking this too.

Stay messy,

Izzy

7 responses to “What Enhertu Side Effects Actually Feel Like (From Inside My Body)”

  1. mshibdonssciencelab Avatar

    You are doing the hard work . Be messy. Be sad. Be angry. Be whatever you need to be at any given moment. Know that you are loved and that you matter, sweetie! Hugs galore from your old momma! 🩷

    Like

  2. alwayselectronic06c81330f4 Avatar
    alwayselectronic06c81330f4

    I love you. Always be you. Never wrong for feeling how you feel Sent from my iPhone

    Like

  3. Abigail Johnston Avatar

    Having just transitioned off Enhertu in the last few months after 18 months of it, your description is so very familiar. It’s not an easy medication. It was also quite effective for me in the time I was on it. Hoping for many many effective treatments for you and that your quality of life stabilizes. Holding space for you.

    Liked by 1 person

  4. fancybutteryca5e75a896 Avatar
    fancybutteryca5e75a896

    Yes 😳

    Liked by 1 person

  5. fancybutteryca5e75a896 Avatar
    fancybutteryca5e75a896

    It’s a hard treatment because there no end of it unless it isn’t working . I did my 10 th tx today . Nausea is the worst it will really start Mon Ontario’s wears off . I work full time as it only me now . I go to work right after tx on Thursday and Friday then off the weekend and right back at the next week the get fluids mid week from nausea .

    Liked by 1 person

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I’m Izzy

Welcome to mojo and the mess, This isn’t the blog I ever expected to write — but it’s the one I needed.

I’m Izzy, a twenty-something living (and dying) with terminal cancer, navigating the messy, heartbreaking, unexpectedly beautiful in-between. Here, you’ll find raw reflections, real talk, dog snuggles (shoutout to Mojo), and the unfiltered truth about what it’s like to face the end of your life before it really got going.

This space is for the ones who’ve felt forgotten, the ones who don’t know what to say, and the ones who are still holding on. It’s not always pretty, but it’s always honest.

Thanks for being here. You’re part of the mess now — and I mean that in the best way.

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